A signature ability is an ability that can only be possessed by members of one evolutionary line.
With the large number of abilities in the main series games and the comparatively small number of Pokémon in Pokémon Uranium, it is not uncommon for a canon ability to be exclusive to one line in Pokémon Uranium despite multiple Pokémon having it in the official games. Due to the large number of such instances, these abilities will currently not be included in this list.
List of Signature Abilities
|Aroma Veil||Protects allies from attacks that limit their move choices.||Normal Ability|
|Atomizate||Normal-type moves become Nuclear-type moves.||Normal Ability|
|Chernobyl||Summons a nuclear fallout when it enters battle.||Gamma form|
|Deep Freeze||Contact with the Pokémon may freeze the attacker.||Normal Ability|
|Disenchant||Grants the bearer immunity to damaging Fairy-type moves.||Hidden Ability|
|Elementalist||Powers up Fire, Electric, and Water-type moves.||Normal Ability|
|Energizate||Normal-type moves become Electric-type moves.||Normal Ability|
|Lazy||Starts the battle sleeping.||Normal Ability|
|Rebuild||Restores HP when not damaged on turn.||Normal Ability|
|Sharp Coral||Doubles Attack and Special Attack, but halves Defense and Special Defense.||Normal Ability|
|Sound Boost||Sound based moves do more damage.||Normal Ability|
|Stormbringer||Summons a thunderstorm when it enters battle.||Normal Ability|